Stat3 Inhibitor I, S3I-201

SKU
S-2444
  • CAS:501919-59-1
  • Formula:C16H15NO7S
  • MW:365.36
  • Appearance:Off-White Solid
  • Purity:97% by HPLC
Product Name Qty
Stat3 Inhibitor I, S3I-201
25 mg
$387.28
Stat3 Inhibitor I, S3I-201
5 mg
$96.82
Inhibits Stat3.Stat3 complex formation and Stat3-DNA binding activity in vitro (IC= 86 33 M) and Stat3-dependent transcriptional activities. S3I-201 inhibits the expression of the Stat3-regulated genes encoding cyclin D1, Bcl-xL, and survivin and inhibits the growth of human breast tumors in vivo.
More Information
Alternate Name/Synonyms
2-Hydroxy-4-[[[[4-methylphenyl)sulfonyl]oxy]acetyl]amino]-benzoic acid; NSC 74859; S3I-201
SKU
S-2444
CAS #
501919-59-1
Chemical Name
2-Hydroxy-4-[[[[4-methylphenyl)sulfonyl]oxy]acetyl]amino]-benzoic acid; NSC 74859; S3I-201
Chemical Formula
C16H15NO7S
Molecular Weight
365.36
Appearance
Off-White Solid
Purity
97% by HPLC
Solubility
DMSO (10 mg/ml)
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
S3I-201 inhibits the expression of the Stat3-regulated genes encoding cyclin D1, Bcl-xL, and survivin and inhibits the growth of human breast tumors
MDL NUMBER
MFCD09907564
CHEMACX
X1851054-4
INCHI
InChI=1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21)
SMILES
Cc1ccc(cc1)S(=O)(=O)OCC(=O)Nc2ccc(c(c2)O)C(=O)O
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
HandlingProtect from air and light
UN #'SNot Applicable
Packing GroupNot Applicable
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