Sterigmatocystin

SKU
S-1094
  • CAS:10048-13-2
  • Formula:C18H12O6
  • MW:324.3 Da
  • Appearance:Light yellow needles
  • Purity:>99%

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Product Name Qty
Sterigmatocystin, Aspergillus Versicolor
5 mg - inquire
$0.00
Sterigmatocystin, Aspergillus Versicolor
10 mg - inquire
$0.00

Mycotoxin that inhibits DNA synthesis. Induces sister chromatid exchanges in bone marrow cells of mice. Causes necrosis. ST exerts a marked influence on gastric mucus and gland cells, showing dominant gastritis, erosion events, polyps, and intestinal metaplasia in these animals.1 Long-term administration of the fungus toxin, sterigmatocystin, induces intestinal metaplasia and increases the proliferative activity of PCNA, p53, and MDM2 in the gastric mucosa of aged Mongolian gerbils. M Kusunoki, J Misumi, et al, Jul 2011; 16(4): 224-31.

 

Isolated from Aspergillus versicolor

More Information
Alternate Name/Synonyms
Sterigmatocystine; 3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furol[3′,2′:4,5]furo[2,3-c]xanthen-7-one; NSC 201423; NSC 204985
SKU
S-1094
CAS #
10048-13-2
Chemical Name
(3S,7R)-15-hydroxy-11-methoxy-6,8,20-trioxapentacyclo[10.8.0.02,9.03,7.014,19]icosa-1,4,9,11,14,16,18-heptaen-13-one
Chemical Formula
C18H12O6
Molecular Weight
324.3 Da
Appearance
Light yellow needles
Purity
>99%
Solubility
Acetone: clear colorless solution at 5 mg/mL acetone
Melting Point
245°C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological disorders
USE
Sterigmatocystin is a carcinogenic compound that affects several species of crops and several species of experimental animals. Chemical structures of sterigmatocystin and aflatoxin B1 are similar. These mycotoxins are pathogens of animals and cereals, producing a major economic impact on biotechnology and agricultural and food industries.
Handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.
Certificate of Analysis 1
Certificate of Analysis 2
GHS PICTOGRAMS
Handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.
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