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BIBR 1532

SKU
B-2377
  • CAS:321674-73-1
  • Formula:C21 H17 N O3
  • MW:331.36
  • Appearance:Solid
  • Purity:98%
Product Name Qty
BIBR 1532
10 mg
$181.11
BIBR 1532
50 mg
$746.09
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Selective telomerase inhibigtor (ICvalues are 93, 100000 and 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively). Causes telomere shortening in exponentially growing NCl-H460 lung carcinoma cells and eventual growth arrest.
More Information
Alternate Name/Synonyms
2-[[(2E)-3(2-Naphtalenyl)-1-oxo-2-butenyl1-yl]amino]benzoic acid
SKU
B-2377
CAS #
321674-73-1
Chemical Name
2-[[(2E)-3(2-Naphtalenyl)-1-oxo-2-butenyl1-yl]amino]benzoic acid
Chemical Formula
C21 H17 N O3
Molecular Weight
331.36
Appearance
Solid
Purity
98%
Solubility
Soluble to 100nM in DMSO and to 25 mM in ethanol
Storage Temp
Room Temp
THERAPEUTIC AREA
Oncological Disorders
USE
Telomerase inhibition by non-nucleosidic compound BIBR1532 causes rapid cell death in pre-B acute lymphoblastic leukemia cells
MDL NUMBER
MFCD11112195
CHEMACX
X1763947-3
INCHI
InChI=1S/C21H17NO3/c1-14(16-11-10-15-6-2-3-7-17(15)13-16)12-20(23)22-19-9-5-4-8-18(19)21(24)25/h2-13H,1H3,(H,22,23)(H,24,25)/b14-12+
SMILES
C/C(=CC(=O)NC1=CC=CC=C1C(=O)O)/C2=CC3=CC=CC=C3C=C2
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
GHS PICTOGRAMS
UN #'S Not Applicable
Packing Group Not Applicable
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