TDZD-8, GSK-3 Beta Inhibitor I

SKU
T-1132
  • CAS:327036-89-5
  • Formula:C10H10N2SO2
  • MW:222.3 Da
  • Appearance:Off-white powder
  • Purity:95% HPLC

2

0

1

Product Name Qty
TDZD-8,GSK-3 Beta Inhibitor I
5 mg
$148.07
TDZD-8 is a highly selective, non-ATP competitive inhibitor of GSK-3b (IC50=2M). TDZD-8 Binds to the active site of GSK3b. TDZD-8 Does not significantly affect the activities of Cdk-1/cyclin B, CK-II, PKA, and PKC (IC50100M). Potential Alzheimer's treatment.
More Information
SKU
T-1132
CAS #
327036-89-5
Chemical Name
4-Benzyl-2-methyl-1,2,4,-thiadiazolidine-3,5-dione
Chemical Formula
C10H10N2SO2
Molecular Weight
222.3 Da
Appearance
Off-white powder
Purity
95% HPLC
Solubility
DMSO
Preparation
Following reconstitution, aliquote at freeze at -20C. Stock solutions can store < 3 months at -20C.
Storage Temp
+4°C
THERAPEUTIC AREA
Neurological disorders
USE
TDZD-8 is a highly selective, non-ATP competitive inhibitor of GSK-3b.Potential Alzheimer's treatment
MDL NUMBER
MFCD04973552
CHEMACX
X1437396-7
INCHI
InChI=1S/C10H10N2O2S/c1-11-9(13)12(10(14)15-11)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3
SMILES
Cn1c(=O)n(c(=O)s1)Cc2ccccc2
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Store in a tightly-sealed vial. Protect from light!
Certificate of Analysis 1
GHS PICTOGRAMS
Handling Store in a tightly-sealed vial. Protect from light!
UN #'S Not Applicable
Packing Group Not Applicable
To Top