Terrein

SKU
T-2611
  • CAS:582-46-7
  • Formula:C8H10O3
  • MW:154.2
  • Appearance:Light tan solid
  • Purity:>95% by HPLC
Product Name Qty
Terrein
1 mg
$221.41
Terrein
5 mg
$773.74
*Please inquire the availability for this product. Terrein is a polar, substituted dihydrocyclopentenone first reported by Raistrick and colleagues in the 1930s and subsequently found in a number of Aspergillus and Penicillium species. For many years the biological profile and mode of action of terrein was unstudied; however, recent research showed that terrein reduces melanin synthesis by reducing tyrosinase production via ERK activation, followed by MITF down-regulation. Terrein also reduces human keratinocyte proliferation by inhibiting ERK and by decreasing the expression of cyclin B1 and Cdc2 complex.
More Information
Alternate Name/Synonyms
(+) Terrein, NSC 291308
SKU
T-2611
CAS #
582-46-7
Chemical Formula
C8H10O3
Molecular Weight
154.2
Appearance
Light tan solid
Purity
>95% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Terrein is a bioactive fungal metabolite that has plant growth inhibition and antibacterial activities
MDL NUMBER
MFCD09752761
INCHI
InChI=1S/C8H10O3/c1-2-3-5-4-6(9)8(11)7(5)10/h2-4,7-8,10-11H,1H3/b3-2+/t7-,8+/m0/s1
SMILES
O=C1\C=C(\C=C\C)[C@H](O)[C@@H]1O
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