TG003

SKU
T-2456
  • CAS:300801-52-9
  • Formula:C13H15NO2S
  • MW:249.33
  • Appearance:Pale yellow Solid
  • Purity:98% by TLC
Product Name Qty
TG003
5 mg
$108.21
TG003
25 mg
$415.76
Cell-permeable. A potent, specific, reversible, and ATP-competitive inhibitor of Cdc2-like kinase (Clk) (K = 10 nM for mClk1/Sty; IC= 20 nM, 200 nM, 10 M, and 15 nM for mClk1, mClk2, mClk3, and mClk4, respectively). Recently, it has been shown that TG003 promotes the skipping of exon 31 in the endogenous dystrophin gene in a dose-dependent manner and increases the production of the dystrophin protein.
More Information
Alternate Name/Synonyms
(Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one
SKU
T-2456
CAS #
300801-52-9
Chemical Name
(Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one
Chemical Formula
C13H15NO2S
Molecular Weight
249.33
Appearance
Pale yellow Solid
Purity
98% by TLC
Solubility
Soluble in DMSO (30 mg/ml)
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Cell-permeable. A potent, specific, reversible, and ATP-competitive inhibitor of Cdc2-like kinase (Clk)
MDL NUMBER
MFCD00624584
CHEMACX
X1460813-4
INCHI
InChI=1S/C13H15NO2S/c1-4-14-11-8-10(16-3)5-6-12(11)17-13(14)7-9(2)15/h5-8H,4H2,1-3H3/b13-7-
SMILES
CCN1c2cc(ccc2S/C1=CC(=O)C)OC
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
Handling Protect from air and light
UN #'S Not Applicable
Packing Group Not Applicable
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