- Appearance:White powder
Thalidomide binds to the E3 ubiquitin ligase complex formed between CRBN, DDB1 and Cul4A inhibiting ligase activity. Inhibits TNFα synthesis and FGF-induced angiogenesis. Cell permeable.
Caution: Teratogenic. Pregnant women should avoid using this compound.
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product.|
|UN #'S||UN 2811|