Thiolutin

SKU
T-1226
  • CAS:87-11-6
  • Formula:C8H8N2O2S2
  • MW:228.29
  • Appearance:Brilliant yellow needle like crystals.
  • Purity:98%
Product Name Qty
Thiolutin
1 mg
$68.34
Thiolutin
5 mg
$267.69

Thiolutin is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. It was found to inhibit in vitro RNA synthesis directed by all three yeast RNA polymerases (I, II, and III). Thiolutin is also an inhibitor of mannan and glucan formation in Saccharomyces cerevisiae and used for the analysis of mRNA stability.

More Information
Alternate Name/Synonyms
Farcinicin, Propiopyvothine, Acetopyrrothine
SKU
T-1226
CAS #
87-11-6
Chemical Name
N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)
Chemical Formula
C8H8N2O2S2
Molecular Weight
228.29
Appearance
Brilliant yellow needle like crystals.
Purity
98%
Solubility
Soluble in Dichloromethane or Methanol, DMSO (0.5%). 1 mg/ml of Thiolutin in DMSO gives a clean orange solution.
Melting Point
184.48 °C
Storage Temp
+4°C
THERAPEUTIC AREA
Infectious Diseases
USE
Thiolutin is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases
MDL NUMBER
MFCD01076610
CHEMACX
X1191506-1
INCHI
InChI=1S/C8H8N2O2S2/c1-4(11)9-6-7-5(3-13-14-7)10(2)8(6)12/h3H,1-2H3,(H,9,11)
SMILES
CC(=O)Nc1c-2sscc2n(c1=O)C
RTECS
JP1355000
UN #'S
UN 2811
PACKING GROUP
II
Handling
Protect from Light
Certificate of Analysis 1
Handling Protect from Light
UN #'S UN 2811
Packing Group II
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