Tigecycline

SKU
T-2461
  • CAS:220620-09-7
  • Formula:C29H39N5O8
  • MW:586.65 Da
  • Appearance:Off-white to yellow-brown solid
  • Purity:98% by HPLC

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Product Name Qty
Tigecycline
5 mg
$74.04
Tigecycline
25 mg
$301.86
A glycylglycine type of antibiotic derived from tetracycline. Inhibits protein translation in bacteria by binding to the 30S ribosomal subunit and blocking entry of amino-acyl tRNA molecules into the A site of the ribosome. This prevents incorporation of amino acid residues into elongating peptide chains.
More Information
Alternate Name/Synonyms
N-[(5aR,6aS,7S,9Z,10aS)-9-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-1,10a,12-trihydroxy-8,10,11-trioxo-5,5a,6,6a,7,8,9,10,10a,11-decahydrotetracen-2-yl]-2-(tert-butylamino)acetamide
SKU
T-2461
CAS #
220620-09-7
Chemical Name
N-[(5aR,6aS,7S,9Z,10aS)-9-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-1,10a,12-trihydroxy-8,10,11-trioxo-5,5a,6,6a,7,8,9,10,10a,11-decahydrotetracen-2-yl]-2-(tert-butylamino)acetamide
Chemical Formula
C29H39N5O8
Molecular Weight
586.65 Da
Appearance
Off-white to yellow-brown solid
Purity
98% by HPLC
Solubility
DMSO (~3 mg/mL with warming)
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious diseases
USE
Tigecycline is an antibiotic, have activity against a variety of Gram-positive and Gram-negative bacterial infection
MDL NUMBER
MFCD00935753
CHEMACX
X1608630-3
INCHI
InChI=1S/C29H39N5O8/c1-28(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30)41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36/h10,12,14,21,31,36,38-39,42H,8-9,11H2,1-7H3,(H2,30,41)(H,32,35)/t12-,14-,21-,29-/m0/s1
SMILES
CC(C)(C)NCC(=O)NC1=CC(=C2C[C@H]3C[C@H]4[C@@H](C(=C(C(=O)[C@]4(C(=C3C(=O)C2=C1O)O)O)C(=O)N)O)N(C)C)N(C)C
Peptide sequence
Not Applicable
RTECS
QI7619500
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
GHS PICTOGRAMS
Handling Protect from light and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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