TM-2-51 | HDAC8 activator

SKU
T-2823
  • CAS:4921-82-8
  • Formula:C14H12N2OS
  • MW:256.32
  • Appearance:Off-white solid
  • Purity:98% by TLC NMR (Conforms)
Product Name Qty
TM-2-51 | HDAC8 activator
50 mg
$207.48

TM-2-51 (4921-82-8) is a highly potent and isozyme selective activator of recombinant HDAC8. Increases the activity of HDAC8 by a factor of 12 at 10 μM. No activation of other HDACs is observed. TM-2-51 rescues the activity of catalytically compromised HDAC8 mutants in vitro.

More Information
SKU
T-2823
CAS #
4921-82-8
Chemical Name
1-Benzoyl-3-phenyl-2-thiourea
Chemical Formula
C14H12N2OS
Molecular Weight
256.32
Appearance
Off-white solid
Purity
98% by TLC NMR (Conforms)
Solubility
Soluble in DMSO (greater than 50 mg/ml) or in Ethanol (up to 8 mg/ml).
Stability
Stable for 1 year as supplied. Solutions in DMSOor ethanol may be stored at -20° for up to 3 months.
Storage Temp
-20°
USE
HDAC8 activator
Hazard Image
Yes
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