Trichostatin C

SKU
T-1174
  • CAS:68676-88-0
  • Formula:C23H32N2O8
  • MW:464.5 Da
  • Appearance:White powder
  • Purity:>95% by HPLC

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Product Name Qty
Trichostatin C
2.5 mg
$1,032.01
Trichostatin C
0.5 mg
$303.53

Description

Trichostatin C is the first example of a glucopyranosyl hydroxamate from nature. The conjugation may act to protect the less stable N-OH group of Trichostatin A. Trichostatin C displays antifungal, antiprotozoan and antitumor activity, albeit less active than trichostatin A.

Isolated from Streptomyces sp.



Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
SKU
T-1174
CAS #
68676-88-0
Chemical Name
(2E,4E)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide
Chemical Formula
C23H32N2O8
Molecular Weight
464.5 Da
Appearance
White powder
Purity
>95% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Trichostatin C is a fungistatic antibiotic.
MDL NUMBER
MFCD08061903
CHEMACX
X6952278-5
INCHI
InChI=1S/C23H32N2O8/c1-13(11-14(2)19(28)15-6-8-16(9-7-15)25(3)4)5-10-18(27)24-33-23-22(31)21(30)20(29)17(12-26)32-23/h5-11,14,17,20-23,26,29-31H,12H2,1-4H3,(H,24,27)/b10-5+,13-11+/t14?,17-,20-,21+,22-,23+/m1/s1
SMILES
O=C(c1ccc(N(C)C)cc1)C(/C=C(/C=C/C(=O)NO[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO)C)C
Handling
Handle in accordance with good industrial hygiene and safety practice.
Handling Handle in accordance with good industrial hygiene and safety practice.
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