Triciribine

SKU
T-2467
  • CAS:35943-35-2
  • Formula:C13H16N6O4
  • MW:320.3
  • Appearance:Pale yellow Solid
  • Purity:98% by HPLC
Product Name Qty
Triciribine
1 mg
$153.79
Cell-permeable. A synthetic tricyclic nucleoside which acts as a specific inhibitor of the Akt signaling pathway. It selectively inhibits the phosphorylation and activation of Akt1, -2 and -3 but does not inhibit Akt kinase activity nor known upstream Akt activators such as PI 3-Kinase and PDK1.
More Information
Alternate Name/Synonyms
1,5-Dihydro-5-methyl-1-b-D-ribofuranosyl-1,2,5,6,8-pentaazanaphthylen-3-amine; NSC 154020
SKU
T-2467
CAS #
35943-35-2
Chemical Name
1,5-Dihydro-5-methyl-1-b-D-ribofuranosyl-1,2,5,6,8-pentaazanaphthylen-3-amine; NSC 154020
Chemical Formula
C13H16N6O4
Molecular Weight
320.3
Appearance
Pale yellow Solid
Purity
98% by HPLC
Solubility
DMSO
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Triciribine, also known as API-2, suppresses the phosphorylation level and kinase activity of Akt
MDL NUMBER
MFCD00932413
CHEMACX
X1035902-9
INCHI
InChI=1S/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/m1/s1
SMILES
CN1c2c3c(cn(c3ncn2)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)C(=N1)N
Peptide sequence
Not Applicable
RTECS
RY8455000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and moisture
Handling Protect from air and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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