Trolox is a water-soluble derivative of vitamin E with potent antioxidant properties. Trolox applications includes standard in antioxidant assays, quenches reactive oxygen species (ROS), as well as,blocks lipid peroxidation. Inhibits peroxynitrite mediated tyrosine nitration and mitochondrial proton permeability
• can quench free radicals (antioxidant activity) • ability to reduce cytotoxicity of Microcystis aeruginosa and microcystin-LR in Artemia franciscana nauplii.
Soluble in DMSO or ethanol (25 mg/mL), or water at alkaline pH
Trolox quenches free radicals and inhibits methylmercury (MeHg)-induced reactive oxygen species (ROS) generation in C6 glial cells. It has been used to determine the total antioxidant capacity of different fruit species through 6--hydroxy-2,5,7,8-tetramethyl chromane-2-carboxylic acid equivalent antioxidant assay (TEAC).