UNC0638

SKU
U-2473
  • CAS:1255580-76-7
  • Formula:C30H47N5O2
  • MW:509.72
  • Appearance:Off-white solid
  • Purity:≥98% by HPLC
Product Name Qty
UNC0638
1 mg
$142.38
UNC0638
5 mg
$541.06
Cell-permeable. UNC0638 is a potent G9a HMTase inhibitor, exhibiting an IC50 value of 50 value of 19 nM, but is more than 10,000-fold selective against SET7/9 (a H3K4 HMTase), SET8 (a H4K20 HMTase), PRMT3, and SUV39H2. UNC0638 inhibits H3K9 dimethylation in MDA-MB231 cells with an IC50 value of 81 nM and demonstrates favorable separation of functional and toxic effect.
More Information
SKU
U-2473
CAS #
1255580-76-7
Chemical Name
2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine
Chemical Formula
C30H47N5O2
Molecular Weight
509.72
Appearance
Off-white solid
Purity
≥98% by HPLC
Solubility
DMSO (10 mM)
Storage Temp
-20°C
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