USP14 Inhibitor, IU1

SKU
U-2474
  • CAS:314245-33-5
  • Formula:C18H21FN2O
  • MW:300.37
  • Appearance:White to off-white Solid
  • Purity:98% by HPLC

2

0

0

Product Name Qty
USP14 Inhibitor, IU1
25 mg
$284.77
USP14 Inhibitor, IU1
5 mg
$83.75
A cell-permeable, reversible and selective inhibitor of the deubiquitinating activity of human USP14 (IC= 4-5 M). IU1 promotes cell survival during proteotoxic stress and selectively stimulates ubiquitin-dependent protein degradation in vitro at 34M.
More Information
Alternate Name/Synonyms
1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-ethanone
SKU
U-2474
CAS #
314245-33-5
Chemical Name
1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-ethanone
Chemical Formula
C18H21FN2O
Molecular Weight
300.37
Appearance
White to off-white Solid
Purity
98% by HPLC
Solubility
DMSO (~20 mg/ml)
Storage Temp
+4°C
USE
IU1 is an inhibitor of USP14, a deubiquitinating enzyme associated with the proteasome
MDL NUMBER
MFCD01917473
CHEMACX
X2815842-9
INCHI
InChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3
SMILES
Cc1cc(c(n1c2ccc(cc2)F)C)C(=O)CN3CCCC3
RTECS
Not Applicable
Handling
Protect from air and light
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
GHS PICTOGRAMS
Handling Protect from air and light
To Top