1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-ethanone
314245-33-5
300.4
C18H21FN2O
DMF, DMSO, Ethanol
-20°C
IU1 is a cell-permeable, reversible and selective inhibitor of the deubiquitinating activity of human USP14 (IC= 4-5 M). IU1 promotes cell survival during proteotoxic stress and selectively stimulates ubiquitin-dependent protein degradation in vitro at 34M.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
