Validamycin A

SKU
V-2489
  • CAS:37248-47-8
  • Formula:C20H35NO13
  • MW:497.5
  • Appearance:White solid
  • Purity:>95% by HPLC
Product Name Qty
Validamycin A
5 mg
$216.43
Validamycin A
25 mg
$756.35
*Please inquire the availability for this product. Validamycin A is the major analogue of a family of cyclitol disaccharides isolated from Streptomyces hygroscopicus var. limoneus by researchers at Takeda in 1970. Although commonly regarded as an aminoglycoside, validamycin shares little in common with conventional aminoglycosides such as streptomycin and gentamicin. Validamycin A is a potent antifungal agent and is used to control fungi in crop production. Validamycin A acts as a potent inhibitor of trehalase, an important enzyme in carbohydrate storage and ultilisation in fungi.
More Information
Alternate Name/Synonyms
Antibiotic T 7545A
SKU
V-2489
CAS #
37248-47-8
Chemical Name
(1S-(1ALPHA,4ALPHA,5BETA,6ALPHA))-1,5,6-TRIDEOXY-3-O-BETA-D-GLUCOPYRANOSYL-5-(HYDROXYMETHYL)-1-((4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-2-CYCLOHEXEN-1-YL) AMINO)-D-CHIRO-INOSITOL
Chemical Formula
C20H35NO13
Molecular Weight
497.5
Appearance
White solid
Purity
>95% by HPLC
Solubility
Soluble in water, methanol, DMSO, DMF, ethanol (slightly), and acetone (slightly) Insoluble in ethyl acetate, and diethyl ether
Melting Point
130-135 °C
Storage Temp
-20
USE
Validamycin A is a potent antifungal agent and is used to control fungi in crop production
MDL NUMBER
MFCD09028089
INCHI
InChI=1S/C20H35NO13/c22-3-6-1-8(12(26)15(29)11(6)25)21-9-2-7(4-23)19(17(31)13(9)27)34-20-18(32)16(30)14(28)10(5-24)33-20/h1,7-32H,2-5H2/t7-,8+,9+,10-,11+,12+,13+,14-,15+,16+,17-,18-,19-,20+/m1/s1
SMILES
C1[C@@H]([C@H]([C@@H]([C@H]([C@H]1N[C@H]2C=C([C@@H]([C@@H]([C@H]2O)O)O)CO)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)CO
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