Virginiamycin complex

SKU
V-2501
  • CAS:11006-76-1
  • Formula:C28H35N3O7 (for M1), C43H49N7O10 (for S1)
  • MW:525.6 (for M1); 823.9 (for S1)
  • Appearance:White solid
  • Purity:>99% by HPLC (75% Virginamycin M1, 20% Virginiamycin S1, 5% Other minor analogues)
Product Name Qty
Virginiamycin complex
5 mg
$355.39
Virginiamycin complex
25 mg
$1,243.86
*Please inquire the availability for this product. Virginiamycin complex is defined as a mixture of 75% ostreogrycin A (virginiamycin M1) and 25% virginiamycin S1, together with the less abundant S analogues. As the two major components have quite different solubilities, these proportions are not readily achieved or used. The composition of the complex is important as Virginiamycin S1 acts a synergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A.
More Information
Alternate Name/Synonyms
Cebin V, Eskalin V, Eskamicin, Stafac, Stephylomycin, Mikamycin, Ostreogrycin, Patricin, Pristinamycin, Streptogramin, Vernamycin.
SKU
V-2501
CAS #
11006-76-1
Chemical Name
N-[(6R,9S,10R,13S,15AS,22S,24AS)-22-BENZYL-6-ETHYL-10,23-DIMETHYL-5,8,12,15,17,21,24-HEPTAOXO-13-PHENYLDOCOSAHYDRO-12H-PYRIDO[2,1-F]PYRROLO[2,1-L][1,4,7,10,13,16]OXAPENTAAZACYCLONONADECIN-9-YL]-3-HYDR OXY-2-PYRIDINECARBOXAMIDE - (10R,11R,12Z,17Z,19Z,21S)-
Chemical Formula
C28H35N3O7 (for M1), C43H49N7O10 (for S1)
Molecular Weight
525.6 (for M1); 823.9 (for S1)
Appearance
White solid
Purity
>99% by HPLC (75% Virginamycin M1, 20% Virginiamycin S1, 5% Other minor analogues)
Solubility
Soluble in DMF, DMSO, ethanol (limited), methanol (limited), and water (poor)
Storage Temp
-20
MDL NUMBER
MFCD01778146
INCHI
InChI=1S/C43H49N7O10.C28H35N3O7/c1-4-29-40(56)49-21-12-17-30(49)41(57)48(3)32(23-26-13-7-5-8-14-26)42(58)50-22-19-28(51)24-31(50)37(53)47-35(27-15-9-6-10-16-27)43(59)60-25(2)34(38(54)45-29)46-39(55)36-33(52)18-11-20-44-36;1-17(2)26-19(4)9-10-24(34)29-11-5-7-18(3)13-20(32)14-21(33)15-25-30-22(16-37-25)27(35)31-12-6-8-23(31)28(36)38-26/h5-11,13-16,18,20,25,29-32,34-35,52H,4,12,17,19,21-24H2,1-3H3,(H,45,54)(H,46,55)(H,47,53);5,7-10,13,16-17,19-20,26,32H,6,11-12,14-15H2,1-4H3,(H,29,34)/b;7-5+,10-9+,18-13+/t25-,29-,30+,31+,32?,34+,35+;19-,20-,26-/m11/s1
SMILES
CC[C@@H]1C(=O)N2CCC[C@H]2C(=O)N(C(C(=O)N3CCC(=O)C[C@H]3C(=O)N[C@H](C(=O)O[C@ @H]([C@@H](C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CC6=CC=CC=C6)C.C[C@@H] 1/C=C/C(=O)NC/C=C/C(=C/[C@H](CC(=O)CC2=NC(=CO2)C(=O)N3CCC=C3C(=O)O[C@@H]1C(C )C)O)/C
GHS PICTOGRAMS
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