Virginiamycin S1

SKU
V-2503
  • CAS:23152-29-6
  • Formula:C43H49N7O10
  • MW:823.9
  • Appearance:White solid
  • Purity:>99% by HPLC

Starting at $355.39

Product Name Qty
Virginiamycin S1
5 mg
$355.39
Virginiamycin S1
25 mg
$1,243.86
*Please inquire the availability for this product. Virginiamycin S1 is one of a family of depsipeptide antibiotics co-produced with ostreogrycin A and used as a synergistic mixture. Virginiamycin S1, also known as Staphylomycin S and Factor S among other synonyms, was discovered independently and named by several groups, leading to considerable confusion in the literature. Virginiamycin S1 acts a synergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A. Virginiamycin S1 differs from virginiamycin B in lacking the dimethylamino moiety on the phenyl ring.
More Information
Alternate Name/Synonyms
Staphylomycin S, PA 114B2, 899, A1745Z3B, Factor S
SKU
V-2503
CAS #
23152-29-6
Chemical Name
N-[(6R,9S,10R,13S,15AS,22S,24AS)-22-BENZYL-6-ETHYL-10,23-DIMETHYL-5,8,12,15,17,21,24-HEPTAOXO-13-PHENYLDOCOSAHYDRO-12H-PYRIDO[2,1-F]PYRROLO[2,1-L][1,4,7,10,13,16]OXAPENTAAZACYCLONONADECIN-9-YL]-3-HYDR OXY-2-PYRIDINECARBOXAMIDE
Chemical Formula
C43H49N7O10
Molecular Weight
823.9
Appearance
White solid
Purity
>99% by HPLC
Melting Point
240-242 °C
Storage Temp
-20
THERAPEUTIC AREA
Infectious Diseases
USE
Antibiotic that inhibits bacterial protein synthesis.
MDL NUMBER
MFCD00864857
INCHI
InChI=1S/C43H49N7O10/c1-4-29-40(56)49-21-12-17-30(49)41(57)48(3)32(23-26-13-7-5-8-14-26)42(58)50-22-19-28(51)24-31(50)37(53)47-35(27-15-9-6-10-16-27)43(59)60-25(2)34(38(54)45-29)46-39(55)36-33(52)18-11-20-44-36/h5-11,13-16,18,20,25,29-32,34-35,52H,4,12,17,19,21-24H2,1-3H3,(H,45,54)(H,46,55)(H,47,53)/t25-,29-,30+,31+,32+,34+,35+/m1/s1
SMILES
CC[C@@H]1C(=O)N2CCC[C@H]2C(=O)N([C@H](C(=O)N3CCC(=O)C[C@H]3C(=O)N[C@H](C(=O)O[C@@H]([C@@H](C(=O)N1)NC(=O)c4c(cccn4)O)C)c5ccccc5)Cc6ccccc6)C
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