VX-702

SKU
V-2481
  • CAS:479543-46-9
  • Formula:C19H12F4N4O2
  • MW:404.32
  • Appearance:White soild
  • Purity:99% by HPLC
Product Name Qty
VX-702
1 mg
$336.03
VX-702
5 mg
$1,019.47
A p38 MAP kinase inhibitor. VX-702 dose-dependently inhibited the production of IL-6, IL-1 and TNF (IC= 59, 122 and 99 ng/ml, respectively). Pre-incubation of platelets with VX-702 (1 M) completely or partially inhibited platelet agonist induced p38 activation (IC= 4 to 20 nM).
More Information
Alternate Name/Synonyms
2-(2,4-Difluorophenyl)-6-(1-(2,6-difluorophenyl)ureido)nicotinamide
SKU
V-2481
CAS #
479543-46-9
Chemical Name
2-(2,4-Difluorophenyl)-6-(1-(2,6-difluorophenyl)ureido)nicotinamide
Chemical Formula
C19H12F4N4O2
Molecular Weight
404.32
Appearance
White soild
Purity
99% by HPLC
Solubility
DMSO
Stability
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Inflammatory Diseases
USE
VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis
MDL NUMBER
MFCD11616590
CHEMACX
X1829255-4
INCHI
InChI=1S/C19H12F4N4O2/c20-9-4-5-10(14(23)8-9)16-11(18(24)28)6-7-15(26-16)27(19(25)29)17-12(21)2-1-3-13(17)22/h1-8H,(H2,24,28)(H2,25,29)
SMILES
C1=CC(=C(C(=C1)F)N(C2=NC(=C(C=C2)C(=O)N)C3=C(C=C(C=C3)F)F)C(=O)N)F
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and moisture
Promo text for AGS discount
N/A
Handling Protect from air and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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