Janex-1

SKU

W-2482

CAS:202475-60-3
Formula:C₁₆H₁₅N₃O₃
MW:297.31
Appearance:White to off-white Solid
Purity:98% by TLC

SDS

CofA

Product Name	Qty
Janex-1 5 mg $139.59
Janex-1 25 mg $441.11

Details

Cell-permeable. Selectively inhibits the tyrosine kinase activity of Jak3 with an ICvalue of 78 M without affecting the enzymatic activity of JAK1, JAK2, or other protein tyrosine kinases. Also helps to induce rat bone marrow stromal cells (MSCs) to neuronal cells.

Specifications

More Information

Alternate Name/Synonyms

4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol,WHI-P131

SKU

W-2482

CAS #

202475-60-3

Chemical Name

4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol

Chemical Formula

C₁₆H₁₅N₃O₃

Molecular Weight

297.31

Appearance

White to off-white Solid

Purity

98% by TLC

Solubility

DMSO (~50mg/ml

Stability

N/A

Storage Temp

-20°C

THERAPEUTIC AREA

Oncological Disorders

USE

JAK3 kinase inhibitor use in cancer

MDL NUMBER

MFCD01862614

CHEMACX

X1863890-1

INCHI

InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19)

SMILES

COc1cc2c(cc1OC)ncnc2Nc3ccc(cc3)O

Handling

Protect from air and light

Promo text for AGS discount

N/A

Reviews

Safety

Handling	Protect from air and light

Citations