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Janex-1

SKU
W-2482
  • CAS:202475-60-3
  • Formula:C16H15N3O3
  • MW:297.31
  • Appearance:White to off-white Solid
  • Purity:98% by TLC
Product Name Qty
Janex-1
5 mg
$142.38
Janex-1
25 mg
$449.93
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Cell-permeable. Selectively inhibits the tyrosine kinase activity of Jak3 with an ICvalue of 78 M without affecting the enzymatic activity of JAK1, JAK2, or other protein tyrosine kinases. Also helps to induce rat bone marrow stromal cells (MSCs) to neuronal cells.
More Information
Alternate Name/Synonyms
4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol,WHI-P131
SKU
W-2482
CAS #
202475-60-3
Chemical Name
4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol
Chemical Formula
C16H15N3O3
Molecular Weight
297.31
Appearance
White to off-white Solid
Purity
98% by TLC
Solubility
DMSO (~50mg/ml
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
JAK3 kinase inhibitor use in cancer
MDL NUMBER
MFCD01862614
CHEMACX
X1863890-1
INCHI
InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19)
SMILES
COc1cc2c(cc1OC)ncnc2Nc3ccc(cc3)O
Handling
Protect from air and light
Handling Protect from air and light
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