WZB117, Glucose transport inhibitor

SKU
W-2603
  • CAS:1223397-11-2
  • Formula:C20H13FO6
  • MW:368.31
  • Appearance:White solid
  • Purity:98% by TLC NMR (Conforms)
Product Name Qty
WZB117, Glucose transport inhibitor
25 mg
$169.27

WZB117 (1223397-11-2) is an inhibitor of Glucose Transporter 1 (GLUT1). It inhibited cell proliferation in lung cancer A549 cells and breast cancer MCF7 cells with an IC50 of approximately 10 μM. Daily intraperitoneal injection of WZB117 at 10mg/kg resulted in 70% reduction in tumor volume of human A549 lung cancer grafted on nude mice.

More Information
SKU
W-2603
CAS #
1223397-11-2
Chemical Name
3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate)
Chemical Formula
C20H13FO6
Molecular Weight
368.31
Appearance
White solid
Purity
98% by TLC NMR (Conforms)
Solubility
Soluble in DMSO (greater than 25 mg/ml) or in Ethanol (greater than 25 mg/ml)
Stability
Stable for 1 year as supplied. Solutions in DMSO or ethanol may br stored at -20° for up to 2 months.
Storage Temp
-20°
Hazard Image
Yes
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