SDS
CofA
Substrate for granzyme B with increased cell permeability. Also a substrate for caspase-10. Peptide Content: 70-90%.
More Information
Alternate Name/Synonyms
Z-Ile-Glu-Thr-Asp-pNA, Caspase-8 Substrate (Chromogenic), Caspase-10, Granzyme B Substrate (Chromogenic)
SKU
G-1083
Chemical Name
Z-Ile-Glu-Thr-Asp-pNA
Chemical Formula
C33H42N6O13
Molecular Weight
730.7
Appearance
White Lyophilized Powder
Purity
99% (HPLC)
Solubility
Soluble in Water
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Fluorogenic substrate for caspase-8 and granzyme B with increased cell permeability.
MDL NUMBER
MFCD01862570
CHEMACX
X1206334-0
INCHI
InChI=1S/C33H42N6O13/c1-4-18(2)27(38-33(49)52-17-20-8-6-5-7-9-20)31(47)35-23(14-15-25(41)42)29(45)37-28(19(3)40)32(48)36-24(16-26(43)44)30(46)34-21-10-12-22(13-11-21)39(50)51/h5-13,18-19,23-24,27-28,40H,4,14-17H2,1-3H3,(H,34,46)(H,35,47)(H,36,48)(H,37,45)(H,38,49)(H,41,42)(H,43,44)/t18-,19-,23+,24+,27+,28+/m1/s1
SMILES
CC[C@@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)Nc1ccc(cc1)[N+](=O)[O-])NC(=O)OCc2ccccc2
Peptide sequence
Z-ILE-GLU-THR-ASP-PNA
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Store in Tightly Sealed Vial Protect from Moisture.
Hazard Image
Yes
| Handling | Store in Tightly Sealed Vial Protect from Moisture. |
|---|---|
| UN #'S | Not Applicable |
| Packing Group | Not Applicable |
