ZM-447439

SKU
Z-2507
  • CAS:331771-20-1
  • Formula:C29H31N5O4
  • MW:513.6
Product Name Qty
ZM-447439
1 mg
$85.43

Cell-permeable. A selective, ATP-competitive inhibitor of Aurora B kinase in vitro (IC₅₀ values are 50 nM, 250 nM and 1 μM for Aurora B, C and A kinases respectively). Selective over a range of other kinases including cdk1 and PLK1 (IC₅₀ > 10 μM).

More Information
SKU
Z-2507
CAS #
331771-20-1
Chemical Name
N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide
Chemical Formula
C29H31N5O4
Molecular Weight
513.6
Solubility
Soluble in DMSO (25 mg/ml), methanol, water (<1 mg/ml), ethanol (48 mg/ml), DMF (~20 mg/ml), and DMSO:PBS (1:1, pH 7.2) (~0.5 mg/ml).
Melting Point
117-120 °C
MDL NUMBER
MFCD08703125
SMILES
COC1=C(OCCCN2CCOCC2)C=C2N=CN=C(NC3=CC=C(NC(=O)C4=CC=CC=C4)C=C3)C2=C1
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