ZM-447439

SKU
Z-2579
  • CAS:331771-20-1
  • Formula:C29 H31 N5 O4
  • MW:513.595
  • Appearance:Solid
Product Name Qty
ZM-447439
10 mg
$136.69
ZM-447439
5 mg
$91.13

 Aurora B kinase inhibitor

More Information
SKU
Z-2579
CAS #
331771-20-1
Chemical Formula
C29 H31 N5 O4
Molecular Weight
513.595
Appearance
Solid
Solubility
Soluble in DMSO (25 mg/ml), methanol, water (<1 mg/ml) at 25 °C, ethanol (48 mg/ml) at 25 °C, DMF (~20 mg/ml), and DMSO:PBS (1:1, pH 7.2)
Melting Point
117-120 °C
Storage Temp
Room Temp
THERAPEUTIC AREA
Oncological Disorders
USE
The dual Aurora kinase inhibitor ZM447439 prevents anaplastic thyroid cancer cell growth and tumorigenicity
MDL NUMBER
MFCD08703125
CHEMACX
X1579378-1
INCHI
InChI=1S/C29H31N5O4/c1-36-26-18-24-25(19-27(26)38-15-5-12-34-13-16-37-17-14-34)30-20-31-28(24)32-22-8-10-23(11-9-22)33-29(35)21-6-3-2-4-7-21/h2-4,6-11,18-20H,5,12-17H2,1H3,(H,33,35)(H,30,31,32)
SMILES
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5
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