3,4’,5,7-Tetrahydroxyflavone; NSC 407289; NSC 656277; Nimbecetin; Pelargidenolon; Pelargidenon; Populnetin; Rhamnolutein; Rhamnolutin; Robigenin; Swartziol; Trifolitin; Indigo Yellow
520-18-3
286.24
C15H10O6
Methanol
-20°C
Kaempferol is a naturally occurring polyphenol antioxidant that displays a wide range of pharmacological activities, including antioxidant, anti-inflammatory, antimicrobial, anticancer, cardioprotective, neuroprotective, antidiabetic, anti-osteoporotic, estrogenic/antiestrogenic, anxiolytic, analgesic and antiallergic activities.
It reduces cell cycle progression in HT-29 cells. Kaempferol increases chromatin condensation, DNA fragmentation and the number of early apoptotic cells in HT-29 cells in a dose-dependent manner. In addition, kaempferol increases the levels of cleaved caspase-9, caspase-3 and caspase-7 as well as those of cleaved poly (ADP-ribose) polymerase. Moreover, it increases mitochondrial membrane permeability and cytosolic cytochrome c concentrations.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
