4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone; AZD 2281; Ku-0059436
763113-22-0
434.5
C24H23FN4O3
DMSO, EtOH
-20°C
Cell-permeable. A highly potent and selective PARP-inhibitor with ICvalues of 5 nM and 1 nM for PARP-1 and PARP-2, respectively. Olaparib displays standalone activity in BRCA-1 deficient breast cancer cells.
0.1 lbs
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