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5-Methylcytidine, 1 G

Price$ 548.75
  • SKU: M-1106-1GM
  • Pack Size: 1 G
Quantity
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+

4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5- (hydroxymethyl)oxolan2-yl]-5-methylpyrimidin-2-one

2140-61-6

257.25

C10H15N3O5

Water

-20°C


5-Methylcytidine is a modified nucleoside derived from 5-methylcytosineIt has been used in epigenetics research, especially in studies involving DNA methylation processes including genomic imprinting and the control of gene expression and differentiation.
 

The presence of 5-methylcytidine in tRNA and rRNA molecules of a wide variety of organisms was first observed more than 40 years ago. Recent studies in eukaryotes have shown that mRNA modifications such as RNA-editing (conversion of an adenosine base to inosine), N6-adenine methylation (m6A), and 5-methylcytidine can change the coding sequence, alter splicing patterns, or change RNA stability.

5-methylcytidine is a modification that occurs both on DNA and RNA. In eukaryotes, this DNA modification has been extensively studied over the past years, and has been found to play a crucial role in genomic imprinting, X-chromosome inactivation, and suppression of repetitive elements.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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