Adriamycin Hydrochloride

SKU
A-1442
  • CAS:25316-40-9
  • Formula:C27 H29 N O11 . Cl H
  • MW:579.983
  • Appearance:Orange Red Solid
  • Purity:99%

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Hazardous
Product Name Qty
Adriamycin Hydrochloride
25 mg
$295.94

Adriamycin is the most extensively studied of a family of highly fluorescent anthracycline antibiotics produced by several Streptomyces species, first reported in 1967 and later approved for human therapeutic used as an anti-tumor agent for the treatment of a wide range of cancers. Adriamycin has also been reported to exhibit anti-HIV and antibacterial activity. The mode of action of Adriamycin is thought to be due to intercalation of DNA and inhibition of nucleic acid synthesis.

More Information
Alternate Name/Synonyms
Doxorubicin, 14-Hydroxydaunomycin, Adriacin, Adriblastin, Caelyx, Dox, Doxil, Farmiblastina, FI 106, K 1039, KW 125, NSC 123127
SKU
A-1442
CAS #
25316-40-9
Chemical Name
(8S,10S)-10-[(3-AMINO-2,3,6-TRIDEOXY-ALPHA-LYXO-HEXOPYRANOSYL)OXY]-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-8-(HYDROXYACETYL)-1-METHOXY-5,12-NAPHTHACENEDIONE HYDROCHLORIDE
Chemical Formula
C27 H29 N O11 . Cl H
Molecular Weight
579.983
Appearance
Orange Red Solid
Purity
99%
Solubility
Soluble in water, methanol, DMSO, DMF with moderate ethanol solubility
Stability
N/A
Melting Point
203.9-205 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
It is used as anticancer agent
MDL NUMBER
MFCD00077757
CHEMACX
X1014352-9
INCHI
InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
SMILES
C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](Cc3c2c(c4c(c3O)C(=O)c5cccc(c5C4=O)OC)O)(C(=O)CO)O)N)O.Cl
Peptide sequence
Not Applicable
GHS Pictograms
4
RTECS
QI9295900
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Certificate of Analysis 1
/media/upload/pdf/A-1442_A-1442,_B1962.pdf
Certificate of Analysis 2
/media/upload/pdf/A-1442_A-1442,_B1675.pdf
Spec
0
Promo text for AGS discount
N/A
GHS PICTOGRAMS
UN #'S Not Applicable
Packing Group Not Applicable
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