Antimycin A3

SKU
A-2621
  • CAS:522-70-3
  • Formula:C26H36N2O9
  • MW:520.6 Da
  • Appearance:White solid
  • Purity:>98% by HPLC

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Starting at $249.99

Product Name Qty
Antimycin A3
5 mg
$899.99
Antimycin A3
1 mg
$249.99

Antimycin A3 is a homologue of the antimycin complex, first isolated in 1958 from Streptomyces blastimyceticus and coproduced with antimycin A4. Antimycin A3 is a more polar analogue of A1 and A2. Like all antimycins, antimycin A3 is a potent inhibitor of respiration by inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A3 exhibits broad biological activity as an antifungal, anthelmintic, insecticidal, antiviral and antitumor active. Lack of availability of the individual antimycin components has hindered greater understanding of the common and unique molecular targets of the components of the antimycin complex.

More Information
Alternate Name/Synonyms
Blastmycin; Blastomycin; Purothionin; NSC58239,
SKU
A-2621
CAS #
522-70-3
Chemical Name
[(2R,3S,6S,7R,8R)-8-butyl-3-[(3-formamido-2-hydroxybenzoyl)amino]-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate
Chemical Formula
C26H36N2O9
Molecular Weight
520.6 Da
Appearance
White solid
Purity
>98% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility
Melting Point
170 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious diseases, Anti-fungal, Anti-viral, Anti-tumor
USE
For laboratory and research purpose only. Antimycin A3 is a potent inhibitor of respiration by inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A3 exhibits broad biological activity.
MDL NUMBER
MFCD00869273
INCHI
InChI=1S/C26H36N2O9/c1-6-7-9-18-23(37-20(30)12-14(2)3)16(5)36-26(34)21(15(4)35-25(18)33)28-24(32)17-10-8-11-19(22(17)31)27-13-29/h8,10-11,13-16,18,21,23,31H,6-7,9,12H2,1-5H3,(H,27,29)(H,28,32)/t15-,16+,18-,21+,23+/m1/s1
SMILES
CCCC[C@@H]1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)c2cccc(c2O)NC=O)C)OC(=O)CC(C)C
RTECS
NY1502900
UN #'S
UN 2811
PACKING GROUP
II
HAZARD CLASS
Class 6.1
Handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product.
Cat. #
MST-A1444
Handling Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product.
UN #'S UN 2811
Packing Group II
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