Ascomycin, Streptomyces hygroscopicus var ascomyceticus

SKU
A-1258
  • CAS:11011-38-4
  • Formula:C43H69NO12
  • MW:792.0
  • Appearance:White Powder
  • Purity:>99.9%

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Hazardous
Product Name Qty
Ascomycin, Streptomyces hygroscopicus var ascomyceticus
1 mg
$35.00
Ascomycin, Streptomyces hygroscopicus var ascomyceticus
5 mg
$60.00
Ascomycin, Streptomyces hygroscopicus var ascomyceticus
25 mg
$145.00

Ascomycin is an ethyl analog of FK506 with strong immunosuppressant properties. Acts by binding to immunophilins, especially macrophilin-12. It appears that Ascomycin inhibits the production of Th1 (interferon- and IL-2) and Th2 (IL-4 and IL-10) cytokines. Ascomycin acts a calcineurin phosphatase inhibitor (CNPI)1.

 

More Information
Alternate Name/Synonyms
Immunomycin, FK 520, FR 520, FR 900520
SKU
A-1258
CAS #
11011-38-4
Chemical Formula
C43H69NO12
Molecular Weight
792.0
Appearance
White Powder
Purity
>99.9%
Solubility
Solubility: Soluble in DMSO.
Melting Point
163-164‚°C
Storage Temp
-20°C, Store in Tightly Sealed Vial.
Product is stable for 3 years as supplied. Ethanol Stock Solutions (1mg/ml) are stable for up to 3 days at -20°C.
GHS Pictograms
9
Certificate of Analysis 1
/media/upload/pdf/A-1258, G1169.pdf
Certificate of Analysis 2
/media/upload/pdf/A-1258, F1040A.pdf
Certificate of Analysis 3
/media/upload/pdf/A-1258, F1040.pdf
Spec
0
GHS PICTOGRAMS
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