Brefeldin A, BFA

SKU
B-1009
  • CAS:20350-15-6
  • Formula:C16H24O4
  • MW:280.4
  • Appearance:White Powder
  • Purity:98%

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Hazardous
Product Name Qty
Brefeldin A
100 mg
$389.75
Brefeldin A
10 mg
$78.18
Brefeldin A, Eupenicillium brefeldianum
25 mg
$290.35
Berefeldin A is an inhibitor of protein translocation from endoplasmic reticulum (ER) to the Golgi apparatus.Activated Mouse B Cells Lack Expression of Granzyme B
More Information
Alternate Name/Synonyms
1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydroxy-6-methyl-4H-cyclopent[f]oxacyclotridecin-4-one; Decumbin; Ascotoxin; γ,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid λ-lactone; Cyanein; BFA
SKU
B-1009
CAS #
20350-15-6
Chemical Name
1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydroxy-6-methyl-4H-cyclopent[f]oxacyclotridecin-4-one
Chemical Formula
C16H24O4
Molecular Weight
280.4
Appearance
White Powder
Purity
98%
Solubility
MeOH
Melting Point
204-205°C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
BFA can induce apoptosis in Neuroendocrine tumor cells by activating caspase-3, and inhibits cell growth by targeting the cell cycle in prostate cancer cells
Merck Index
Merck Index: 12.1393.1996
MDL NUMBER
MFCD12913297
CHEMACX
X1009661-0
INCHI
InChI=1S/C16H24O4/c1-11-5-3-2-4-6-12-9-13(17)10-14(12)15(18)7-8-16(19)20-11/h4,6-8,11-15,17-18H,2-3,5,9-10H2,1H3/b6-4+,8-7+/t11-,12+,13-,14+,15+/m0/s1
SMILES
C[C@H]1CCC/C=C/[C@@H]2C[C@@H](C[C@H]2[C@@H](/C=C/C(=O)O1)O)O
Peptide sequence
Not Applicable
GHS Pictograms
3
RTECS
GY8410000
UN #'S
UN 3462
PACKING GROUP
III
HAZARD CLASS
Not Applicable
Handling
Warning.Toxic. May be Carcinogenic. Wear gloves/mask when handling product. Avoid contact by all means of exposure.
Certificate of Analysis 1
/media/upload/pdf/B-1009, H1301.pdf
Certificate of Analysis 2
/media/upload/pdf/B-1009, G1111.pdf
Certificate of Analysis 3
/media/upload/pdf/B-1009, E1094C.pdf
Spec
0
GHS PICTOGRAMS
Handling Warning.Toxic. May be Carcinogenic. Wear gloves/mask when handling product. Avoid contact by all means of exposure.
UN #'S UN 3462
Packing Group III
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