Caspase-3 Inhibitor Z-DEVD-FMK

SKU
C-2241
  • Formula:C30H41FN4O12
  • MW:668.7 Da
  • Appearance:Liquid
  • Purity:>98% by HPLC

0

2

0

Product Name Qty
Caspase-3 Inhibitor Z-DEVD-FMK
20 ul
$149.00

Description

Caspase-3 Inhibitor Z-DEVD-FMK is a synthetic peptide inhibitor that irreversibly inhibits caspase-3 and related protease/caspase activity and blocks apoptosis. DEVD is the specific recognition sequence found in poly (ADP-ribose) polymerase (PARP). The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
Z-DEVD-FMK; Caspase-3 inhibitor; Z-DEVD fluoromethylketone
SKU
C-2241
Chemical Name
Sequence: Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK (FMK, fluoromethyl ketone)
Chemical Formula
C30H41FN4O12
Molecular Weight
668.7 Da
Appearance
Liquid
Purity
>98% by HPLC
Storage Temp
-20°C
USE
Irreversibly inhibits caspase-3 and related protease/caspase activity and blocks apoptosis
PubChecm ID
16760394
INCHI
InChI=1S/C30H41FN4O12/c1-17(2)26(29(42)33-20(22(36)15-31)13-24(38)45-4)35-27(40)19(11-12-23(37)44-3)32-28(41)21(14-25(39)46-5)34-30(43)47-16-18-9-7-6-8-10-18/h6-10,17,19-21,26H,11-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,43)(H,35,40)/t19-,20-,21-,26-/m0/s1
SMILES
CC(C)C(C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CCC(=O)OC)NC(=O)C(CC(=O)OC)NC(=O)OCC1=CC=CC=C1
Peptide sequence
Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK
Handling
Protect from light and moisture
Certificate of Analysis 1
Certificate of Analysis 2
Handling Protect from light and moisture
To Top