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(+)-cis,trans-Abscisic Acid

SKU
A-1103
  • CAS:21293-29-8
  • Formula:C15H20O4
  • MW:264.32 Da
  • Appearance:White to light-yellow solid
  • Purity:≥98%
Product Name Qty
(+)-cis,trans-Abscisic Acid
1 g
$174.79
(+)-cis,trans-Abscisic Acid
5 g
$640.89
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Description

(+)-cis,trans-Abscisic acid is a natural, active isomer of a plant hormone. The compound is involved in several roles including seed germination, stress response, embryogenesis, regulation of transpiration, and acts as a signal of reduced water availability. The most effects of ABA seem to be adaptive responses that promote water conservation in plants by reducing water losses and slowing growth. (+)-cis,trans-Abscisic acid is also a plant growth regulator which has high-affinity binding sites on plasmalemma of Vicia faba guard cells. ABA regulates gene expression of hundreds of plant genes through complex interactions of intracellular signaling systems. Seed dormancy, stomatal movement, leaf abscission and plant stress responses are several physiological mechanisms this compound is also involved in.

 

Applications

• In vitro: simulates glucose uptake by myocytes and pre-adipocytes
• In vivo: Stimulates glucose uptake by brown adipose tissue
• Pro-inflammatory modulator of innate immune system cells
• Stimulates human mesenchymal and hematopoietic stem cell proliferation
• Used to control Cas9 via an RNA polymerase-based biosensor

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
Abscisic Acid; (S)-(+)-Abscisic acid; Abscisin II; (+)-Abscisic acid; Dormin; ABA
SKU
A-1103
CAS #
21293-29-8
Chemical Name
(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid
Chemical Formula
C15H20O4
Molecular Weight
264.32 Da
Appearance
White to light-yellow solid
Purity
≥98%
Solubility
No information available
Melting Point
161-162°C
Storage Temp
-20°C, desiccated
THERAPEUTIC AREA
Not Available
USE
Natural isomer of the abscission accelerating plant hormone. For research use only. Not intended for diagnostic or therapeutic use. There are several effects of Abscisic acid: 1) Antitranspirant - Induces stomatal closure, decreasing transpiration to prevent water loss. 2) Inhibits fruit ripening. 3) Responsible for seed dormancy by inhibiting cell growth – inhibits seed germination. 4) Inhibits the synthesis of Kinetin nucleotide. 5) Downregulates enzymes needed for photosynthesis. 6) Acts on endodermis to prevent growth of roots when exposed to salty conditions.
Merck Index
13.594.2001
MDL NUMBER
MFCD00066545
CHEMACX
X1010049-1
PubChecm ID
5280896
INCHI
JLIDBLDQVAYHNE-YKALOCIXSA-N
SMILES
CC1=CC(=O)CC([C@]1(/C=C/C(=CC(=O)O)/C)O)(C)C
RTECS
RZ2475100
Handling
Protect from light. Handle in accordance with good industrial hygiene and safety practice. Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection.
msds 1
A-1103, ABA, SDS, diamond format.pdf
Certificate of Analysis 1
A-1103, L1422.pdf
Certificate of Analysis 2
A-1103, J1023F r01.pdf
Certificate of Analysis 3
A-1103, J1023C.pdf
GHS PICTOGRAMS
HandlingProtect from light. Handle in accordance with good industrial hygiene and safety practice. Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection.
CitationsAbscisic acid transcriptomic signaling varies with grapevine organ
FCA does not bind abscisic acid
Combining chemical and genetic approaches to increase drought resistance in plants
Dehydration stress-induced oscillations in LEA protein transcripts involves abscisic acid in the moss, Physcomitrella patens
Karrikins discovered in smoke trigger Arabidopsis seed germination by a mechanism requiring gibberellic acid synthesis and light
Reporter Gene-Facilitated Detection of Compounds in Arabidopsis Leaf Extracts that Activate the Karrikin Signaling Pathway
Timing of ripening initiation in grape berries and its relationship to seed content and pericarp auxin levels
Involvement of abscisic acid in leaf and root of maize (Zea mays L.) in avoiding chilling-induced water stress
Abscisic acid-responsive guard cell metabolomes of Arabidopsis wild-type and gpa1 G-protein mutants
G protein-coupled receptor-type G proteins are required for light-dependent seedling growth and fertility in Arabidopsis
Transgenic Arabidopsis plants expressing the type 1 inositol 5-phosphatase exhibit increased drought tolerance and altered abscisic acid signaling
The Arabidopsis putative G protein-coupled receptor GCR1 interacts with the G protein alpha subunit GPA1 and regulates abscisic acid signaling
G-protein complex mutants are hypersensitive to abscisic acid regulation of germination and postgermination development
Abscisic acid induces rapid subnuclear reorganization in guard cells
The glycolytic enzyme, phosphoglycerate mutase, has critical roles in stomatal movement, vegetative growth, and pollen production in Arabidopsis thaliana
Sequestration of auxin by the indole-3-acetic acid-amido synthetase GH3-1 in grape berry (Vitis vinifera L.) and the proposed role of auxin conjugation during ripening
Metabolic Signatures in Response to Abscisic Acid (ABA) Treatment in Brassica napus Guard Cells Revealed by Metabolomics
Light, genotype, and abscisic acid affect chloroplast positioning in guard cells of Arabidopsis thaliana leaves in distinct ways
Sugar and abscisic acid signaling orthologs are activated at the onset of ripening in grape
Characterization of wound-responsive RNA-binding proteins and their splice variants in Arabidopsis
Ripening of grape berries can be advanced or delayed by reagents that either reduce or increase ethylene levels
Integrating Molecular and Physiological Aspects of Grape Berry Ripening
Closely related receptor complexes differ in their ABA selectivity and sensitivity
Investigation of plant hormone level changes in shoot tips of longan (Dimocarpus longan Lour.) treated with potassium chlorate by liquid chromatography-electrospray ionization mass spectrometry
Engineering Small Molecule Responsive Split Protein Kinases
Regulatory components of the abscisic acid receptors in Arabidopsis thaliana
Small molecule gated split-tyrosine phosphatases and orthogonal split-tyrosine kinases
Studio degli aspetti nutrizionali e tossicologici di mieli uniflorali
Two novel GPCR-type G proteins are abscisic acid receptors in Arabidopsis
Contribution to the characterisation of honey-based Sardinian product abbamele: Volatile aroma composition, honey marker compounds and antioxidant activity
Local microRNA delivery targets Palladin and prevents metastatic breast cancer
Biodiversity of Salix spp. honeydew and nectar honeys determined by RP-HPLC and evaluation of their antioxidant capacity
Floral markers of strawberry tree (Arbutus unedo L.) honey
Color evaluation of seventeen European unifloral honey types by means of spectrophotometrically determined CIE L*Cab*h(ab)° chromaticity coordinates
Riboflavin and lumichrome in Dalmatian sage honey and other unifloral honeys determined by LC-DAD technique
Single (19)F probe for simultaneous detection of multiple metal ions using miCEST MRI
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