Collagenase, Type 4
- MW:849.474 Da
- Appearance:White to dark brown powder
- Purity:≥160 units per mg dry weight
Prepared to contain lower tryptic activity levels to limit damage to membrane proteins and receptors but with normal to above normal collagenase activity. Suggested for pancreatic islet primary isolation. A dialyzed lyophilized powder.
White to dark brown powder
≥160 units per mg dry weight
Clear colorless solution
Collagenase is a protease that cleaves the bond between a neutral amino acid (X) and glycine in the sequence Pro-X-Glyc-Pro, which is found with high frequency in collagen. Collagenase is unique among proteases in its ability to degrade the triple-helical native collagen fibrils commonly found in connective tissues such as skin, tendon, blood vessels, and bone. Collagenase disaggregation is suitable for the culture of human tumors, mouse kidney, human adult and fetal brain, and many other tissues including epithelium. Collagenase is relatively gentle, dissociates well at physiological temperature and pH, and requires no mechanical agitation or special equipment.
Use personal protective equipment as required. No special handling advices are necessary.
Certificate of Analysis 1
|Handling||Use personal protective equipment as required. No special handling advices are necessary.|