Cytochalasin D (Zygosporin A)

SKU
C-1070
  • CAS:22144-77-0
  • Formula:C30H37NO6
  • MW:507.6 Da
  • Appearance:White powder
  • Purity:≥97%

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Product Name Qty
Cytochalasin D
1 mg
$110.56
Cytochalasin D
5 mg
$432.17

Description:

Cytochalasin D is a cell-permeable fungal toxin, 10-fold more effective than Cytochalasin B. Binds to barbed end of actin filaments, inhibiting the association and dissociation of subunits.

Does not inhibit monosaccharide transport across cell membranes. Cytochalasin D is reported to exhibit antitumor activity, and induce apoptosis.

 

More Cytochalasin Products

• Cytochalasin A (C-1111)
• Cytochalasin B (C-1027)
• Cytochalasin C (C-1200)
• Cytochalasin E (C-1197)
• Cytochalasin H (C-2703)
• Cytochalasin J (C-2705)

 

More Information
Alternate Name/Synonyms
Cytochalasin D; Zygosporin A; Lygosporin A
SKU
C-1070
CAS #
22144-77-0
Chemical Name
[(1R,2R,3E,5R,7S,9E,11R,12S,14S,15R,16S)-16-benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-6,18-dioxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl] acetate
Chemical Formula
C30H37NO6
Molecular Weight
507.6 Da
Appearance
White powder
Purity
≥97%
Solubility
Soluble in DMSO, Ethanol, Methanol
Melting Point
255-260°C
Preparation
N/A
Storage Temp
-20°C
USE
Cytochalasins are used as tools in cytological research, and in the field of actin polymerization. Cytochalasin D is 10 times more effective than cytochalasin B and does not inhibit glucose transport across cell membranes.
Merck Index
12.2859.1996
MDL NUMBER
MFCD00077706
CHEMACX
X1009686-7
INCHI
InChI=1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1
SMILES
C[C@H]1C/C=C/[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C/[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]3Cc4ccccc4)C)O
Peptide sequence
N/A
RTECS
GZ4850000
UN #'S
UN 1544
PACKING GROUP
II
Handling
Protect from moisture. Open carefully. Use the original container to store the product. Avoid exposing to strong direct light.
Certificate of Analysis 1
GHS PICTOGRAMS
Handling Protect from moisture. Open carefully. Use the original container to store the product. Avoid exposing to strong direct light.
UN #'S UN 1544
Packing Group II
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