Cytochalasin E

SKU
C-1197
  • CAS:36011-19-5
  • Formula:C28H33NO7
  • MW:495.6 Da
  • Appearance:White powder
  • Purity:≥98% (HPLC)

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Product Name Qty
Cytochalasin E, Aspergillus clavatus
1 mg
$58.07
Cytochalasin E, Aspergillus clavatus
5 mg
$213.29
Cytochalasin E, Aspergillus clavatus
10 mg
$369.64

Description:

Cytochalasin E is a fungal metabolite that inhibits angiogenesis tumor growth. Enhances PKC-dependent process of secretion. Does not inhibit glucose transport. Isolated from Aspergillus clavatusInhibitor of actin polymerization in blood platelets.

 

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• Cytochalasin H (C-2703)
• Cytochalasin J (C-2705)

More Information
Alternate Name/Synonyms
Cytochalasin E from Aspergillus clavatus; Cytochalasine
SKU
C-1197
CAS #
36011-19-5
Chemical Name
(1S,5E,7R,9S,11E,13S,14S,16R,17S,18S,19S)-19-benzyl-7-hydroxy-7,9,16,17-tetramethyl-2,4,15-trioxa-20-azatetracyclo[11.8.0.01,18.014,16]henicosa-5,11-diene-3,8,21-trione
Chemical Formula
C28H33NO7
Molecular Weight
495.6 Da
Appearance
White powder
Purity
≥98% (HPLC)
Solubility
Soluble in DMSO, ethyl acetate, ethanol, dichloromethane.
Melting Point
225ºC
Preparation
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
N/A
USE
A fungal toxin used in actin polymerization and cytological research. Potent and selective inhibitor of bovine capillary endothelial cell proliferation.
Merck Index
N/A
MDL NUMBER
MFCD00005178
CHEMACX
X1009687-4
INCHI
InChI=1S/C28H33NO7/c1-16-9-8-12-19-23-27(4,35-23)17(2)21-20(15-18-10-6-5-7-11-18)29-24(31)28(19,21)36-25(32)34-14-13-26(3,33)22(16)30/h5-8,10-14,16-17,19-21,23,33H,9,15H2,1-4H3,(H,29,31)/b12-8+,14-13+/t16-,17-,19-,20-,21-,23-,26+,27+,28+/m0/s1
SMILES
C[C@H]1C/C=C/[C@H]2[C@H]3[C@](O3)([C@H]([C@@H]4[C@]2(C(=O)N[C@H]4Cc5ccccc5)OC(=O)O/C=C/[C@@](C1=O)(C)O)C)C
Peptide sequence
N/A
RTECS
HA5360000
UN #'S
UN 2811
PACKING GROUP
II
HAZARD CLASS
Not Applicable
Handling
Warning: Toxic! May be Carcinogenic. Wear gloves/mask when handling product. Avoid contact by all means of exposure. This product should be kept in a tightly closed container. This product should be handled only by qualified experienced professionals. Wash thoroughly after handling this material.
Certificate of Analysis 1
GHS PICTOGRAMS
Handling Warning: Toxic! May be Carcinogenic. Wear gloves/mask when handling product. Avoid contact by all means of exposure. This product should be kept in a tightly closed container. This product should be handled only by qualified experienced professionals. Wash thoroughly after handling this material.
UN #'S UN 2811
Packing Group II
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