Epirubicin Hydrochloride

SKU
E-2306
  • CAS:56390-09-1
  • Formula:C27H29NO11
  • MW:579.98
  • Appearance:Orange-red Powder
  • Purity:95% by HPLC

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Product Name Qty
Epirubicin Hydrochloride
5 mg
$108.21
Epirubicin Hydrochloride
25 mg
$404.38

Cell-permeable. An anthracycline antitumor antibiotic. A stereoisomer of doxorubicin (Cat. No. 1527-5) that exhibits reduced cardiotoxicity. Its antitumor actions are mediated by targeting topoisomerase II.

More Information
Alternate Name/Synonyms
(8S-cis)-10-((3-amino-2,3,6-trideoxy-L-arabino-hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione hydrochloride; 4'-epiadriamycin; 4'-epidoxorubicin
SKU
E-2306
CAS #
56390-09-1
Chemical Name
(8S-cis)-10-((3-amino-2,3,6-trideoxy-β-L-arabino-hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione hydrochloride; 4'-epiadriamycin; 4'-epidoxorubicin
Chemical Formula
C27H29NO11
Molecular Weight
579.98
Appearance
Orange-red Powder
Purity
95% by HPLC
Solubility
Soluble in H2O (1 mg/ml)
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
A cell-permeable Topo II inhibitor used antitumor antibiotic
MDL NUMBER
MFCD00941448
CHEMACX
X1026832-3
INCHI
InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22-,27-;/m0./s1
SMILES
C[C@H]1[C@@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](Cc3c2c(c4c(c3O)C(=O)c5cccc(c5C4=O)OC)O)(C(=O)CO)O)N)O.Cl
RTECS
QI9295750
Handling
Protect from air and moisture
Certificate of Analysis 1
GHS PICTOGRAMS
Handling Protect from air and moisture
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