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Glycine

SKU
G-2585
  • CAS:56-40-6
  • Formula:C2H5NO2
  • MW:75.07 Da
  • Appearance:White crystalline powder
  • Purity:≥98.5%
Product Name Qty
Glycine
5 kg
$209.01
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Description

Glycine is the simplest amino acid and is amphoteric. It can either be protonating or protonated, depending on pH. Because of this property, it is used for buffers.

Glycine is an inhibitory neurotransmitter in CNS and modulates excitatory neurotransmission by potentiating the action of glutamate at N-methyl-D-aspartate (NMDA) receptors. In addition, it has been shown that glycine modulates macrophage effector functions implicated in CNS inflammation and in other related inflammatory conditions.

 

Applications

• Used in preparation of electrophoresis buffers

• Cell culture

• Study of neurotransmitters

 

References

• “Glycine neurotransmitter transporters: an update”

• “The inhibitory neurotransmitter glycine modulates macrophage activity by activation of neutral amino acid transporters.”

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
Aminoacetic acid; Aminoethanoic acid; Glycocoll; Glycolixir; Glycosthene; Aciport; Glicoamin; Padil
SKU
G-2585
CAS #
56-40-6
Chemical Name
2-aminoacetic acid
Chemical Formula
C2H5NO2
Molecular Weight
75.07 Da
Appearance
White crystalline powder
Purity
≥98.5%
Solubility
Soluble in water (100 mg/ml), and acetone (slightly soluble). Insoluble in alcohol, and ether.
Melting Point
240 °C (lit.)(dec.)
Storage Temp
Store at room temperature
THERAPEUTIC AREA
Not Applicable
USE
Glycine is widely used as a buffer for a variety of immunological applications. It is frequently used in the preparation of TG Buffers (Tris-Glycine; sc-296648) where the buffer is used as a running and/or transfer buffer for polyacrylamide gel electrophoresis and western blotting. Glycine (100 mM, pH 2.0-2.5; sc-295018) is also used as an eluent in column chromatography. Glycine has been reported for use in the enzymatic determination of lactate using lactic dehydrogenase.
SMILES
(C(=O)O)N
Handling
Corrosive hazard. Wear protective gloves/clothing and eye/face protection. Handle in accordance with good industrial hygiene and safety practice.
Certificate of Analysis 1
G-2585, L1244.pdf
Certificate of Analysis 2
G-2585, L1187.pdf
Certificate of Analysis 3
G-2585, K1043A with recertifcation date r.01.pdf
GHS PICTOGRAMS
HandlingCorrosive hazard. Wear protective gloves/clothing and eye/face protection. Handle in accordance with good industrial hygiene and safety practice.
CitationsSerum and peritoneal evaluation of vitamin D-binding protein in women with endometriosis
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