Cibacron Blue 3G-A, Sodium Salt [GST Inhibitor-1]
- Formula:C29H17ClN7O11S3 • 3Na
- Appearance:Dark blue powder
- Purity:~60% (dye content)
Cibacron Blue 3G-A, Sodium Salt is an effective inhibitor of Glutathione S-transferase (GST) at a concentration of 2-20 µM. Also known as GST Inhibitor-1.
The dye Cibacron Blue 3G-A is a sulfonated polyaromatic compound that has a high affinity for many proteins and enzymes. In the immobilized form the dye is used as an affinity chromatographic medium to separate and purify a variety of proteins including dehydrogenases, kinases, serum albumin, interferons, several plasma proteins, and a host of other proteins. Cibacron Blue 3G-A displays diversity in binding several unrelated classes of proteins and as a result has been applied in studies as a chromophore itself and also as an immobilized ligand.
In a study Cibacron Blue 3G-A has shown the ability to rapidly, in one step, sequester, concentrate and protect from proteolytic degradation low molecular weight proteins and peptides from serum, thereby allowing the analysis of low-abundance labile biomarkers.
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Protect from light and moisture|