Cibacron Blue 3G-A, Sodium Salt [GST Inhibitor-1]

SKU
G-2344
  • CAS:84166-13-2
  • Formula:C29H17ClN7O11S3 • 3Na
  • MW:840.11
  • Appearance:Dark blue powder
  • Purity:~60% (dye content)
Product Name Qty
Cibacron Blue 3G-A, Sodium Salt [GST Inhibitor-1]
1 g
$138.68

Description

Cibacron Blue 3G-A, Sodium Salt is an effective inhibitor of Glutathione S-transferase (GST) at a concentration of 2-20 µM. Also known as GST Inhibitor-1.

The dye Cibacron Blue 3G-A is a sulfonated polyaromatic compound that has a high affinity for many proteins and enzymes. In the immobilized form the dye is used as an affinity chromatographic medium to separate and purify a variety of proteins including dehydrogenases, kinases, serum albumin, interferons, several plasma proteins, and a host of other proteins. Cibacron Blue 3G-A displays diversity in binding several unrelated classes of proteins and as a result has been applied in studies as a chromophore itself and also as an immobilized ligand.

In a study Cibacron Blue 3G-A has shown the ability to rapidly, in one step, sequester, concentrate and protect from proteolytic degradation low molecular weight proteins and peptides from serum, thereby allowing the analysis of low-abundance labile biomarkers.

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
Cibacron Blue F3GA, Reactive Blue, GST Inhibitor-1, Cibacron blue
SKU
G-2344
CAS #
84166-13-2
Chemical Name
1-amino-4-[4-[[4-chloro-6-(2-sulfoanilino)-1,3,5-triazin-2-yl]amino]-3-sulfoanilino]-9,10-dioxoanthracene-2-sulfonic acid
Chemical Formula
C29H17ClN7O11S3 • 3Na
Molecular Weight
840.11
Appearance
Dark blue powder
Purity
~60% (dye content)
Solubility
Water
Storage Temp
Room temperature
USE
Inhibitor of Glutathione S-transferase (GST)
MDL NUMBER
MFCD00043102
CHEMACX
X1087867-8
INCHI
InChI=1S/C29H20ClN7O11S3/c30-27-35-28(33-16-7-3-4-8-19(16)49(40,41)42)37-29(36-27)34-17-10-9-13(11-20(17)50(43,44)45)32-18-12-21(51(46,47)48)24(31)23-22(18)25(38)14-5-1-2-6-15(14)26(23)39/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37)
SMILES
c1ccc2c(c1)C(=O)c3c(cc(c(c3C2=O)N)S(=O)(=O)O)Nc4ccc(c(c4)S(=O)(=O)O)Nc5nc(nc(n5)Cl)Nc6ccccc6S(=O)(=O)O
Handling
Protect from light and moisture
Certificate of Analysis 1
HandlingProtect from light and moisture
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