Herbimycin A, Streptomyces Hygroscopicus
- MW:574.7 Da
- Appearance:Yellow powder
- Purity:>99% by HPLC
Herbimycin A is a benzoquinoid ansamycin antibiotic isolated from a Streptomyces hygroscopicus. Herbimycin A inhibits the 90-kDa heat-shock protein (Hsp90) which provides essential chaperone support to various signal transduction molecules, including certain steroid hormone receptors and select kinases. Herbimycin also inhibits protein tyrosine kinase and angiogenesis.
|Handling||Warning. Neurotoxin. Ensure adequate ventilation, especially in confined areas. Use personal protective equipment as required. Use with local exhaust ventilation. Do not breathe dust/fume/gas/mist/vapors/spray. Corrosive hazard. Wear protective gloves/clothing and eye/face protection.|