Hygromycin B, Concentrated Solution

  • CAS:31282-04-9
  • Formula:C20H37N3O13
  • MW:527.5 Da
  • Appearance:Light amber colored solution
  • Purity:≥90% (HPLC)

Starting at $106.02

Product Name Qty
Hygromycin B, Concentrated Solution
1 MU
Hygromycin B, Concentrated Solution
5x1 MU

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Hygromycin B is an antibiotic that is known to be effective against bacteria, fungi, viruses and assorted eukaryotic pathogens. As an aminoglycoside antibiotic, hygromycin B inhibits ribosome biogenesis by targeting the 30S ribosomal subunit and preventing translation. As a result, the compound suppresses protein synthesis within pathogenic cells.

AG Scientific's Hygromycin B solution is a sterile-filtrate solution in DI Water.



In clinical practice, hygromycin B can be used to treat bacterial infections. In the laboratory, it is frequently used as a selection antibiotic for pathogens that have developed hygromycin resistance. Research has also shown that the aminoglycoside class of antibiotics can suppress certain mutations, a fact which has been leveraged as a treatment for Duchenne dystrophy.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. Hygromycin's longstanding application as a gene selection antibiotic, has a powerful new role in genome editing utilizing the CRISPR/CAS9 system.


Additional Reading

• Hygromycin B: Frequently Asked Questions


Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
Hygrovetine; Hygrovectine; D-streptamine; Antihelmycin
Chemical Name
Chemical Formula
Molecular Weight
527.5 Da
Light amber colored solution
≥90% (HPLC)
Storage Temp
Store at +4°C
Infectious diseases
Hygromycin B is an antibiotic produced by the bacterium Streptomyces hygroscopicus. It is an aminoglycoside that kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis. Hygromycin resistance gene is frequently used as a selectable marker in research on plants. In rice Agrobacterium-mediated transformation system, hygromycin is used at about 30–75 mg L−1, with an average of 50 mg L−1. The use of hygromycin at 50 mg L−1 demonstrated highly toxic to non-transformed calli. Thus, it can be efficiently used to select transformants.
Merck Index
UN #'S
UN 3462
Warning.Toxic. May be Carcinogenic. May be Teratogenic. Wear gloves/mask when handling product.
Additional Videos
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
HandlingWarning.Toxic. May be Carcinogenic. May be Teratogenic. Wear gloves/mask when handling product.
UN #'SUN 3462
Packing GroupI
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