Kanamycin Sulfate Solution (50 mg/mL)

SKU
K-1023
  • CAS:25389-94-0
  • Formula:C18H36N4O11•H2SO4
  • MW:582.58 Da
  • Appearance:Clear liquid
  • Purity:>95%

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Product Name Qty
Kanamycin Sulfate Solution (50 mg/mL)
100 mL
$71.75
Kanamycin Sulfate Solution (50 mg/mL)
25 mL
$30.75
Kanamycin Sulfate Solution (50 mg/mL)
50 mL
$51.25

Description

Kanamycin is an aminoglycosidic antibiotic that inhibits growth of gram-positive, gram-negative bacteria and mycoplasmas in cell culture. Kanamycin or kanamycin A is a major component of the antibiotic complex produced by certain strains of Streptomyces kanamyceticus. Kanamycin is supplied in two forms, a crystalline monosulfate monohydrate and a salt with a higher sulfate content. Kanamycin sulfate, which is sometimes referred to as “kanamycin bisulfate,” is obtained by adding sulfuric acid to a solution of the monosulfate and drying using a suitable procedure. Kanamycin sulfate binds to 30S ribosomes causing inhibition of bacterial protein synthesis.

 

Applications

• Lab Application - used as a resistance marker to grow plasmids of interest in competent bacterial cells
• Therapeutic Use - used as a second-line anti-tuberculosis drug

More Information
Alternate Name/Synonyms
Kanamycin, Kanamycin A, Kanamycin Bisulfate, Kanamycin sulfate salt solution
SKU
K-1023
CAS #
25389-94-0
Chemical Name
O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine, monosulfate
Chemical Formula
C18H36N4O11•H2SO4
Molecular Weight
582.58 Da
Appearance
Clear liquid
Purity
>95%
Solubility
Water
Storage Temp
Room temperature
THERAPEUTIC AREA
Bacterial infections
USE
Kanamycin Sulfate Solution is used as a selection agent for cells transformed with kanamycin B resistance gene. It is also used as a culture media additive for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium. It can also be used as a selection agent for cells transformed with kanamycin B resistance gene. Indications of kanamycin is short term treatment of bacterial infections caused by the following pathogens: E. coli, Proteus species (both indole-positive and indole-negative), Enterobacter aerogenes, Klebsiella pneumoniae, Serratia marcescens, and Acinetobacter species.
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