Kanamycin Sulfate

SKU
K-1022
  • CAS:25389-94-0
  • Formula:C18H36N4O11•H2SO4
  • MW:582.58 Da
  • Appearance:White to off-white crystalline powder
  • Purity:>95%

2

0

0

Starting at $66.49

Product Name Qty
Kanamycin Sulfate
10 g
$66.49
Kanamycin Sulfate
25 g
$112.07

Description

Kanamycin is an aminoglycosidic antibiotic that inhibits growth of gram-positive, gram-negative bacteria and mycoplasmas in cell culture. Kanamycin or kanamycin A is a major component of the antibiotic complex produced by certain strains of Streptomyces kanamyceticus. Kanamycin is supplied in two forms, a crystalline monosulfate monohydrate and a salt with a higher sulfate content. Kanamycin sulfate, which is sometimes referred to as “kanamycin bisulfate,” is obtained by adding sulfuric acid to a solution of the monosulfate and drying using a suitable procedure. Kanamycin sulfate binds to 30S ribosomes causing inhibition of bacterial protein synthesis.

Applications

Laboratory Use - resistance marker to grow plasmids of interest in competent bacterial cells.

Therapeutic Use - a second-line anti-tuberculosis drug.

Specifications

EC Number: 246-933-9

 

More Information
Alternate Name/Synonyms
Kanamycin; Kanamycin A; Kanamycin Sulfate Salt; Kanamycin monosulfate; Kanamycin acid sulfate; Kantrex, Ophtalmokalixan
SKU
K-1022
CAS #
25389-94-0
Chemical Name
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid
Chemical Formula
C18H36N4O11•H2SO4
Molecular Weight
582.58 Da
Appearance
White to off-white crystalline powder
Purity
>95%
Solubility
Soluble in water
Melting Point
250° C
Preparation
N/A
Storage Temp
Room temperature
THERAPEUTIC AREA
Bacterial infections
USE
Kanamycin A Monosulfate is an antibiotic that belongs to the family of aminoglycosides. The antibiotic associates with ribosomal RNA by forming a complex at the bacterial ribosomal A site. Studies show that when Kanamycin A and Neomycin B (sc-338359) are conjugated through lipid conjugation there is an increase of antibacterial activity against methicillin-resistant Staphylococcus epidermidis (MRSE) from Kanamycin A and methicillin-resistant Staphylococcus aureus (MRSA) from both antibiotics.
Merck Index
13.5299.2001
MDL NUMBER
MFCD00070253
CHEMACX
X1004299-4
PubChecm ID
441374
INCHI
InChI=1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1
SMILES
C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N.OS(=O)(=O)O
RTECS
N/A
Handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Handle in accordance with good industrial hygiene and safety practice. Corrosive hazard. Wear protective gloves/clothing and eye/face protection.
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
GHS PICTOGRAMS
Handling Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Handle in accordance with good industrial hygiene and safety practice. Corrosive hazard. Wear protective gloves/clothing and eye/face protection.
We found other products you might like!
To Top