Monensin Sodium Salt

SKU
M-1211
  • CAS:22373-78-0
  • Formula:C36H61NaO11
  • MW:692.86 Da
  • Appearance:White powder
  • Purity:≥95%

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Product Name Qty
Monensin, Sodium Salt.
1 g
$72.02
Monensin, Sodium Salt.
5 g
$299.87

Description

Na+ ionophore. Forms lipophilic complexes with monovalent cations to induce Na+ influx and H+/K+ efflux. Increases intracellular Ca2+ levels.

Exhibits diverse biological actions; displays antibacterial properties and modulates ion gradients and intracellular pH. Apoptosis inducer. Blocks glycoprotein secretion; inhibits HDL to decrease cellular cholesterol esterification.

Specifications

Product has minimum purity of 95%, inquire if higher purity required.

More Information
Alternate Name/Synonyms
Monensin sodium; Na+ ionophore; Sodium ionophore
SKU
M-1211
CAS #
22373-78-0
Chemical Name
4-[2-[5-Ethyl-5-[5-[6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]- 3-methyloxolan-2-yl]oxolan-2-yl]- 9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid sodium salt
Chemical Formula
C36H61NaO11
Molecular Weight
692.86 Da
Appearance
White powder
Purity
≥95%
Solubility
Soluble in ethanol to 100 mM
Stability
N/A
Melting Point
267-269 °C
Preparation
N/A
Storage Temp
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
THERAPEUTIC AREA
Infectious Diseases
USE
Sodium ionophore. Broad spectrum antiprotozoal, antibacterial and antifungal agent that disrupts protein transport.
Merck Index
N/A
MDL NUMBER
MFCD00077826
CHEMACX
X1009754-0
INCHI
InChI=1S/C36H62O11.Na/c1-10-34(31-20(3)16-26(43-31)28-19(2)15-21(4)36(41,18-37)46-28)12-11-27(44-34)33(8)13-14-35(47-33)17-25(38)22(5)30(45-35)23(6)29(42-9)24(7)32(39)40;/h19-31,37-38,41H,10-18H2,1-9H3,(H,39,40);/q;+1/p-1/t19-,20-,21+,22+,23-,24?,25-,26+,27+,28-,29+,30-,31+,33-,34-,35+,36-;/m0./s1
SMILES
OC[C@]1(O)O[C@@H]([C@@H](C)C[C@H]1C)[C@H]2C[C@H](C)[C@@H](O2)[C@]3(CC)CC[C@@H](O3)[C@]5(C)CC[C@]4(C[C@H](O)C[C@](C)(O4)[C@@H](C)[C@@H](OC)C(C)C(=O)O)O5
Peptide sequence
Not Applicable
RTECS
JH2830000
UN #'S
UN 3462
PACKING GROUP
II
HAZARD CLASS
N/A
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Certificate of Analysis 1
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
UN #'S UN 3462
Packing Group II
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