n-Octyl-Beta-D-Glucopyranoside (OG)

SKU
O-1036
  • CAS:29836-26-8
  • Formula:C14H28O6
  • MW:292.44 Da
  • Appearance:White powder
  • Purity:≥98% (HPLC)

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Starting at $247.23

Product Name Qty
n-Octyl-Beta-D-Glucopyranoside
5 g
$247.23
n-Octyl-Beta-D-Glucopyranoside
25 g
$481.40

Description

n-Octyl-Beta-D-Glucopyranoside (also known as OG) is a non-ionic detergent that has high water solubility, tiny uniform micelles, and a chemical structure that is well-defined. OG can form nanostructures in water that are self-assembled. These properties make OG superior to almost all other types of non-ionic detergents that are used for membrane solubilization.

n-Octyl-Beta-D-Glucopyranoside can also be easily removed by dialysis in comparison to bile salts due to its high critical micelle concentration (20-25 mM). After reconstitution, OG should be kept under sterile conditions and stored at a refrigerated temperature of 4°C. It should be stored under inert gas and tightly sealed. Contact with eyes, skin, and clothing should be avoided.

 

Applications

• n-Octyl-Beta-D-Glucopyranoside is used for solubilizing membrane-bound proteins in their native state
• Used to prepare lipid vesicles
• Used to permeabilize membrane cells of fixed cells that are paraformaldehyde

 

More Information
Alternate Name/Synonyms
B-Octylglucoside; N-Octyl glucoside; OGP; BOP
SKU
O-1036
CAS #
29836-26-8
Chemical Name
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-octoxyoxane-3,4,5-triol
Chemical Formula
C14H28O6
Molecular Weight
292.44 Da
Appearance
White powder
Purity
≥98% (HPLC)
Solubility
Clear, colorless solution (100 mg/ml in water)
Melting Point
103-104 °C
Preparation
N/A
Storage Temp
-20°C, desiccated
THERAPEUTIC AREA
Not Available
USE
n-Octyl-Beta-D-Glucopyranoside is a non-ionic detergent which has been used for isoelectric focusing (IEF) and two-dimensional electrophoresis (2D). It has been shown to be superior to Triton™ X-100 for IEF of plant proteins and it has also been used for concentration of protein from 2D gels for digestion and mass spectroscopy analysis.
Merck Index
N/A
MDL NUMBER
MFCD00063288
CHEMACX
X1016705-8
INCHI
InChI=1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1
SMILES
CCCCCCCCO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.
msds 1
/media/upload/pdf/O-1036, 1-O-Octyl-beta-D-glucopyranoside, SDS, diamond format.pdf
Certificate of Analysis 1
/media/upload/pdf/O-1036, J1299.pdf
Certificate of Analysis 2
/media/upload/pdf/O-1036, J1255.pdf
Certificate of Analysis 3
/media/upload/pdf/O-1036, J1062.pdf
Handling Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.
UN #'S Not Applicable
Packing Group Not Applicable
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