Novobiocin

SKU
N-2613
  • CAS:303-81-1
  • Formula:C31H36N2O11
  • MW:612.6 Da
  • Appearance:Pale yellow solid
  • Purity:>95% by HPLC

2

0

0

Product Name Qty
Novobiocin
5 mg
$148.07
Novobiocin
25 mg
$517.14

Description

Novobiocin is an aminocoumarin antibiotic isolated from a number of Streptomyces species. Novobiocin exhibits broad spectrum Gram-positive antibiotic activity and was used clinically. Novobiocin is a potent inhibitor of bacterial DNA gyrase and a competitive inhibitor of the ATPase reaction catalysed by GyrB.

 

More Information
Alternate Name/Synonyms
Streptonivicin; Inamycin; Cardelmycin; Spheromycin; Albamycin; Cathomycin; Crystallinic acid; Vulcamycin; PA 93; WS 6629; Griseoflavin; S 800
SKU
N-2613
CAS #
303-81-1
Chemical Name
[(3R,4S,5R,6R)-5-hydroxy-6-[4-hydroxy-3-[[4-hydroxy-3-(3-methylbut-2-enyl)benzoyl]amino]-8-methyl-2-oxochromen-7-yl]oxy-3-methoxy-2,2-dimethyloxan-4-yl] carbamate
Chemical Formula
C31H36N2O11
Molecular Weight
612.6 Da
Appearance
Pale yellow solid
Purity
>95% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases, Gram-Positive Bacterial Infection
USE
Novobiocin exhibits broad spectrum Gram positive antibiotic activity. Potent bacterial DNA gyrase inhibitor.
MDL NUMBER
MFCD00072100
INCHI
InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1
SMILES
Cc1c(ccc2c1oc(=O)c(c2O)NC(=O)c3ccc(c(c3)CC=C(C)C)O)O[C@H]4[C@@H]([C@@H]([C@H](C(O4)(C)C)OC)OC(=O)N)O
Handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.Further processing of solid materials may result in the formation of combustible dusts. The potential for combustible dust formation should be taken into consideration before additional processing occurs.
GHS PICTOGRAMS
Handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols.Further processing of solid materials may result in the formation of combustible dusts. The potential for combustible dust formation should be taken into consideration before additional processing occurs.
To Top