Oridonin

SKU
O-2374
  • CAS:28597-04-2
  • Formula:C20H28N5O6
  • MW:364.43
  • Appearance:Off-White Solid
  • Purity:97% by HPLC
Product Name Qty
Oridonin
5 mg
$79.74
Oridonin
25 mg
$283.63
Oridonin, a diterpenoid isolated from Rabdosia rubescens displays anti-inflammatory, anti-bacterial, anti-tumor effects and has been used for the treatment of human cancers, especially esophageal carcinoma. Exposure to oridonin induces apoptosis in AE (AML1-ETO)-bearing leukemic cells through the activation of intrinsic apoptotic pathway and triggering a caspase-3-mediated degradation of AE at D188
More Information
Alternate Name/Synonyms
NSC-250682
SKU
O-2374
CAS #
28597-04-2
Chemical Name
(1S,4AR,5S,11AS,11BS,14S)-1,5,6,14-TETRAHYDROXY-4,4-DIMETHYL-8-METHYLENEDECAHYDRO-1H-6,11B-(EPOXYMETHANO)-6A,9-METHANOCYCLOHEPTA[A]NAPHTHALEN-7(8H)-ONE
Chemical Formula
C20H28N5O6
Molecular Weight
364.43
Appearance
Off-White Solid
Purity
97% by HPLC
Solubility
DMSO
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Oridonin induces apoptosis, inhibits migration and invasion on highly-metastatic human breast cancer
MDL NUMBER
MFCD00221762
CHEMACX
X1273057-7
INCHI
InChI=1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11,14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3
SMILES
CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C
Peptide sequence
Not Applicable
RTECS
NZ8177000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and moisture
Handling Protect from air and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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