13408-56-5
464.6
C27H44O6
Acetic acid, Ethanol, Methanol, DMSO
-20°C
Ponasterone A is an off-white powder that is part of the ecdysteroid family. It has properties that are similar to muristerone A. It is a steroid hormone in insects that plays a role in regulating metamorphosis. Ponasterone A is a powerful gene expression regulator that rapidly activates and deactivates reporter genes in cells and transgenic organisms.
Ponasterone A is an ecdysone A analog and can function as an economical and reliable substitute for muristerone A. It acts as an ecdysone-inducible mammalian expression system inducer. It is a very bioactive ligand in vivo, displaying continual release and transgene expression.
Applications:
- Regulation of gene expression
- Can increase cell number at G1 phase while also inhibiting cell growth
- Enables reporter genes to be turned off and on rapidly
- Researchers have used Ponasterone A for studies on iron-related conditions, various cancers in humans, and neurodegenerative diseases
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
