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Cefpodoxime (Free Acid), 5 G

Price$ 662.75
  • SKU: C-1475-5GM
  • Pack Size: 5 G
Quantity
-
+

Cefpodoxima; Cefpodoximum

80210-62-4

427.46

C15H17N5O6S2

DMSO

-20°C


Cefpodoxime (free acid) is a metabolite of Cefpodoxime proxetil and a third generation cephalosporin anti-bacterial that is active against both Gram-positive and negative bacteria. Its effect is to inhibit synthesis of bacterial cell wall. Cephalosporins are a type of β-lactam antibiotic that prevents the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins.
 

It is stable towards the most commonly found plasmid-mediated β-lactamases. The in vitro inhibitory activity of it is little affected by the addition of plasma serum or the type of testing medium used; however, increasing the inocula size more than 106 cfu/mL reduced the potency of the drug against β-lactamase producing strains of Enterobacteriaceae.

It is reported that Cefpodoxime proxetil has a postantibiotic effect of up to 2 hours against Gram-positive species, although it was without effect against Gram-negative species.


Applications:

  • Antibiotic for gram-positive and gram-negative bacteria
  • Antimicrobial susceptibility test

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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