Stylomycin hydrochloride; 3′-[α-Amino-p methoxyhydrocinnamamido]-3′-deoxy-N,Ndimethyladenosine dihydrochloride
58-58-2
544.4
C22H29N7O5 • 2HCl
Water
-20°C
Puromycin Dihydrochloride is an aminoglycoside antibiotic that is isolated from Streptomyces alboniger. Puromycin acts as a protein synthesis inhibitor by incorporating itself into a polypetide chain that has been growing, causing it to prematurely terminate. Puromycin’s primary application is as a gene-selection antibiotic with an important role in gene-editing via CRISPR/Cas9.
This puromycin reagent, which is in the form of hydrochloride salt, has antineoplastic, antitrypanosomal, and antimicrobial properties. It is important to keep Puromycin Dihydrochloride stored in a tightly closed container in a well-ventilated and dry area.
Applications:
- Selective antibiotic agent for cell culture systems, selection of mammalian cell lines
- Protein synthesis inhibitor
- Studies of regulatory mechanisms which control specific gene functions during cell differentiation
- Can be used for specific types of cancer therapy
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
